HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: AHR (P35869)
Aryl hydrocarbon receptor (Ah receptor) (AhR) (Class E basic helix-loop-helix protein 76) (bHLHe76)
Gene: AHR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

The method score is based on:

Property	Details
Experiments	9712901, 10644764, 18524851, 11259609
Identification Methods	affinity chromatography technology, two hybrid, pull down, two hybrid array
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription and 4 others more... GO:0045892 - negative regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050728 - negative regulation of inflammatory response GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	928
Hs

1	848

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024