Protein: GPTC8
G patch domain-containing protein 8

Gene: GPTC8, GPATCH8
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q9UKJ3

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1128146

DHX8
ATP-dependent RNA helicase DHX8

2

8

High-throughput

0.737

High

1145431

RNPS1
RNA-binding protein with serine-rich domain 1

5

6

Small-scale

0.713

High

889832

CLK3
Dual specificity protein kinase CLK3

4

10

High-throughput

0.704

High

1346976

SNIP1
Smad nuclear-interacting protein 1

4

1

High-throughput

0.691

High

1461106

LC7L2
Putative RNA-binding protein Luc7-like 2

4

4

High-throughput

0.691

High

211447

RFOX2
RNA binding protein fox-1 homolog 2

3

4

High-throughput

0.667

High

1446684

LUC7L
Putative RNA-binding protein Luc7-like 1

3

4

High-throughput

0.667

High

1308330

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.638

High

1335401

CAMKV
CaM kinase-like vesicle-associated protein

4

3

High-throughput

0.636

High

685767

U2AF2
Splicing factor U2AF 65 kDa subunit

2

6

High-throughput

0.628

High

889677

CLK2
Dual specificity protein kinase CLK2

2

10

High-throughput

0.628

High

1239384

ESRP1
Epithelial splicing regulatory protein 1

2

5

High-throughput

0.628

High

807614

IF4A3
Eukaryotic initiation factor 4A-III

1

10

High-throughput

0.618

High

1133038

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

12

High-throughput

0.618

High

1311888

DHX40
Probable ATP-dependent RNA helicase DHX40

1

8

High-throughput

0.618

High

1414617

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

High-throughput

0.618

High

872047

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

2

High-throughput

0.604

High

1395088

JPH4
Junctophilin-4

3

2

High-throughput

0.604

High

350754

NOE2
Noelin-2

2

0

High-throughput

0.602

High

480345

RU1C
U1 small nuclear ribonucleoprotein C

2

1

High-throughput

0.601

High

485755

RU2A
U2 small nuclear ribonucleoprotein A'

2

6

High-throughput

0.601

High

1006786

SRPK2
SRSF protein kinase 2

2

14

High-throughput

0.601

High

260591

BRD4
Bromodomain-containing protein 4

2

19

High-throughput

0.584

High

373452

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

217540

E41L2
Band 4.1-like protein 2

2

14

High-throughput

0.574

High

1461105

E41L3
Band 4.1-like protein 3

2

14

High-throughput

0.574

High

397183

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1433650

E41L1
Band 4.1-like protein 1

2

14

High-throughput

0.549

High

134902

SAP18
Histone deacetylase complex subunit SAP18

1

2

High-throughput

0.536

High

886608

CTCF
Transcriptional repressor CTCF

1

6

High-throughput

0.536

High

1006955

KC1G2
Casein kinase I isoform gamma-2

1

4

High-throughput

0.536

High

1051532

SRS11
Serine/arginine-rich splicing factor 11

1

7

High-throughput

0.536

High

1062149

SRSF4
Serine/arginine-rich splicing factor 4

1

5

High-throughput

0.536

High

1099595

SRSF6
Serine/arginine-rich splicing factor 6

1

8

High-throughput

0.536

High

1435432

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1451414

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

2

High-throughput

0.536

High

1458275

IKBL1
NF-kappa-B inhibitor-like protein 1

1

1

High-throughput

0.536

High

1461108

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

1

High-throughput

0.536

High

1461109

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.536

High

522004

H14
Histone H1.4

1

5

High-throughput

0.515

High

591880

H2AX
Histone H2AX

1

8

High-throughput

0.515

High

1120384

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

6

High-throughput

0.515

High

1208908

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.515

High

1372336

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.515

High

927604

ATX1
Ataxin-1

1

7

High-throughput

0.508

High

964502

SUMO2
Small ubiquitin-related modifier 2

1

9

High-throughput

0.501

High

1416946

KLF16
Krueppel-like factor 16

1

15

High-throughput

0.500

High

911957

JAK3
Tyrosine-protein kinase JAK3

1

11

High-throughput

0.489

High

1384153

ARRD3
Arrestin domain-containing protein 3

1

13

High-throughput

0.489

High

505625

ATX1L
Ataxin-1-like

1

7

High-throughput

0.481

High

159911

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

4

High-throughput

0.479

High

364008

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.479

High

406780

MYCN
N-myc proto-oncogene protein

1

19

High-throughput

0.479

High

414814

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

473169

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.479

High

595637

H15
Histone H1.5

1

5

High-throughput

0.479

High

607205

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

636162

CD11B
Cyclin-dependent kinase 11B

1

8

High-throughput

0.479

High

696826

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

765984

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.479

High

775366

FUS
RNA-binding protein FUS

1

8

High-throughput

0.479

High

905271

MECP2
Methyl-CpG-binding protein 2

1

12

High-throughput

0.479

High

971268

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

980518

H4
Histone H4

1

9

High-throughput

0.479

High

1005231

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.479

High

1017287

H33
Histone H3.3

1

20

High-throughput

0.479

High

1033303

EWS
RNA-binding protein EWS

1

7

High-throughput

0.479

High

1045892

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

1048127

TLE3
Transducin-like enhancer protein 3

1

12

High-throughput

0.479

High

1083456

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.479

High

1127233

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

1150018

TERF2
Telomeric repeat-binding factor 2

1

4

High-throughput

0.479

High

1258972

H32
Histone H3.2

1

20

High-throughput

0.479

High

1276943

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.479

High

1329934

SIR6
NAD-dependent protein deacylase sirtuin-6

1

10

High-throughput

0.479

High

1351192

SP7
Transcription factor Sp7

1

16

High-throughput

0.479

High

1367550

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1368413

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1369867

CELF1
CUGBP Elav-like family member 1

1

1

High-throughput

0.479

High

1387629

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

1401060

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

1405454

FEV
Protein FEV

1

4

High-throughput

0.479

High

1412834

PCGF1
Polycomb group RING finger protein 1

1

16

High-throughput

0.479

High

1437235

NANOG
Homeobox protein NANOG

1

8

High-throughput

0.479

High

1446430

BRD7
Bromodomain-containing protein 7

1

11

High-throughput

0.479

High

1448783

RNC
Ribonuclease 3

1

6

High-throughput

0.479

High

1459257

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1461103

CD11A
Cyclin-dependent kinase 11A

1

8

High-throughput

0.479

High

1461107

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

335933

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.458

High

1244842

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1357172

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1364008

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

574506

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

High-throughput

0.445

High

974077

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.445

High

1460997

FBW1B
F-box/WD repeat-containing protein 11

1

12

High-throughput

0.445

High

1461110

NUMBL
Numb-like protein

1

1

High-throughput

0.439

High

769479

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.437

High

1054666

PSME1
Proteasome activator complex subunit 1

1

3

High-throughput

0.437

High

1227675

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.437

High

1339024

NUP43
Nucleoporin Nup43

1

19

High-throughput

0.437

High

1434196

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1445964

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

7

High-throughput

0.437

High

1461102

PSME2
Proteasome activator complex subunit 2

1

3

High-throughput

0.437

High

1461104

FBW1A
F-box/WD repeat-containing protein 1A

1

12

High-throughput

0.437

High

973845

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.426

High

922793

CCHL
Holocytochrome c-type synthase

2

0

High-throughput

0.318

High

1331876

SYT2
Synaptotagmin-2

2

0

High-throughput

0.313

High

518574

ADX
Adrenodoxin, mitochondrial

1

0

High-throughput

0.279

Low

1143815

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.279

Low

1419579

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

1438522

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

1384651

APH1A
Gamma-secretase subunit APH-1A

1

0

High-throughput

0.251

Low

1339222

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025