HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CCNJL (Q8IV13)
Cyclin-J-like protein
Gene: CCNJL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 297 Hs			1 435
+	Hs
		625508 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNJL_HUMAN (1-435): 9.19e-143: 416: 100.00
+	Hs
		625487 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNJ_HUMAN (2-435): 1.63e-94: 291: 37.56
+	Hs
		303829 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNB2_HUMAN (3-338): 8.71e-88: 274: 17.34
+	Hs
		538471 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNB1_HUMAN (4-334): 8.51e-85: 267: 18.18
+	Hs
		303821 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		CCNB2_HUMAN (3-338): 8.71e-88: 274: 17.34
+	Hs
		538521 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		CCNB1_HUMAN (4-334): 8.51e-85: 267: 18.18
+	Hs
		414711 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		CCNB1_HUMAN (4-334): 8.51e-85: 267: 18.18
+	Mm
		509465 CDK1_MOUSE (1-297): 4.35e-142: 403: 96.97		CCNB1_MOUSE (4-338): 6.58e-83: 262: 16.81
+	Hs
		625350 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNA1_HUMAN (4-329): 4.02e-72: 236: 18.32
+	Xl
		526765 CDK1A_XENLA (1-296): 1.57e-141: 402: 87.50		CCNB1_XENLA (3-336): 1.12e-75: 243: 15.99
+	Hs
		414855 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		CCNA1_HUMAN (4-329): 4.02e-72: 236: 18.32
+	Gg
		533892 CDK1_CHICK (1-296): 5.72e-141: 400: 92.23		CCNB2_CHICK (3-336): 1.7e-71: 232: 16.57
+	Mm
		956329 CDK2_MOUSE (1-297): 2.06e-140: 401: 55.94		CCNA1_MOUSE (8-331): 1.47e-69: 228: 19.03
+	Hs
		625194 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNF_HUMAN (4-378): 8.43e-54: 193: 12.20
+	Hs
		590125 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CCNA2_HUMAN (8-331): 3.13e-53: 185: 17.83
+	Hs
		414800 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		CCNF_HUMAN (4-378): 8.43e-54: 193: 12.20
+	Hs
		590162 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		CCNA2_HUMAN (8-331): 3.13e-53: 185: 17.83
+	Hs
		414732 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		CCNA2_HUMAN (8-331): 3.13e-53: 185: 17.83
+	Mm
		509476 CDK1_MOUSE (1-297): 4.35e-142: 403: 96.97		CCNA2_MOUSE (4-326): 9.91e-54: 186: 17.88
+	Mm
		851183 CDK2_MOUSE (1-297): 2.06e-140: 401: 55.94		CCNA2_MOUSE (4-326): 9.91e-54: 186: 17.88