Interactor 1: TOP1 (P04786)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (Maintenance of killer protein 1)
Gene: TOP1

Interactor 2: NOP53 (Q12080)
Ribosome biogenesis protein NOP53 (Nucleolar protein 53)
Gene: NOP53

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.481

The method score is based on:

Property Details
Experiments 22875988
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 769
Sc

1 455
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025