Interactor 1: TOP1 (P06612)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (Omega-protein) (Relaxing enzyme) (Swivelase) (Untwisting enzyme)
Gene: topA

Interactor 2: RECQ (P15043)
ATP-dependent DNA helicase RecQ (EC 5.6.2.4) (DNA 3'-5' helicase RecQ)
Gene: RECQ

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 19402753, 15690043
Identification Methods tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Toprim
Common GO terms GO:0003677 - DNA binding
GO:0005694 - chromosome
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 865
Ec

1 609
+ Hs
+ Hs
+ Hs
+ Hs
+ Xl
+ Dm
+ Ce
+ Sc
+ Sp
+ Ec

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Last updated: 15 Jul 2024