HitPredict

Interactor 1: AT1A1 (P06685)
Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)
Gene: Atp1a1

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	32357304
Identification Methods	cross-linking study, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0019901 - protein kinase binding GO:0030424 - axon GO:0051087 - protein-folding chaperone binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1023 Rn			1 752
+	Rn
		94112 AT1A1_RAT (1-1023): 0: 1091: 100.00		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		416169 AT1A3_RAT (28-1023): 0: 1036: 86.95		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94114 AT1A3_RAT (28-1023): 0: 1036: 86.95		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		416161 AT1A2_RAT (1-1023): 0: 1034: 86.12		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94113 AT1A2_RAT (1-1023): 0: 1034: 86.12		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		392995 AT1A1_HUMAN (1-1023): 0: 1080: 96.77		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496196 AT1A3_HUMAN (27-1023): 0: 1038: 87.06		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496589 AT1A2_HUMAN (1-1023): 0: 1036: 85.92		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Rn
		513722 AT2A2_RAT (42-1014): 0: 790: 26.63		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94131 AT2A2_RAT (42-1014): 0: 790: 26.63		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Mm
		223146 AT2A2_MOUSE (42-1014): 0: 791: 26.63		TAU_MOUSE (1-752): 1.92e-82: 279: 89.52
+	Hs
		496237 AT2A2_HUMAN (42-1014): 0: 790: 26.73		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		561576 AT2A2_HUMAN (42-1014): 0: 790: 26.73		MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08