Interactor 1: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2

Interactor 2: ESC2 (Q06340)
Protein ESC2 (Establishes silent chromatin protein 2)
Gene: ESC2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.55 0.617

The method score is based on:

Property Details
Experiments 12399377, 25631822, 18757937
Identification Methods two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0030466 - silent mating-type cassette heterochromatin formation
GO:0031507 - heterochromatin formation
Homologous interactions 0

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Last updated: 15 Jul 2024