HitPredict

Interactor 1: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 978 Sc			1 693
+	Sc
		695283 ORC1_YEAST (1-975): 0: 754: 23.77		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		416270 SIR3_YEAST (1-978): 0: 937: 100.00		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		416269 SIR3_YEAST (1-978): 0: 937: 100.00		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		494686 ORC1_YEAST (1-975): 0: 754: 23.77		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		492101 ORC1_YEAST (1-975): 0: 754: 23.77		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Hs
		503551 RFC1_HUMAN (129-771): 6.79e-26: 117: 12.24		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		695287 ORC4_YEAST (490-896): 8.62e-16: 83.5: 8.37		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		694611 RFC1_YEAST (265-769): 2.54e-14: 79.7: 10.46		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		494689 ORC4_YEAST (490-896): 8.62e-16: 83.5: 8.37		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		492104 ORC4_YEAST (490-896): 8.62e-16: 83.5: 8.37		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		493855 RFC1_YEAST (265-769): 2.54e-14: 79.7: 10.46		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		491087 RFC1_YEAST (265-769): 2.54e-14: 79.7: 10.46		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55