Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Interactor 2: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 9418880, 27864334, 29987188, 16648488, 16541103, 24248602, 24971752, 8521827, 18955708, 22509910, 26186194, 28514442, 25923732, 25940091, 30573685, 10600798, 7651417, 10753870, 24981860, 33961781 and 13 others

more...

Identification Methods affinity chromatography technology, pull down, protein complementation assay, far western blotting, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001662 - behavioral fear response
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 6 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 217
Hs

1 1599
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Ce
+ At
+ Sc
+ Sc
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024