Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Interactor 2: 4EBP2 (Q13542)
Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2)
Gene: EIF4EBP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 32296183, 7935836, 25416956, 26186194, 20347422, 28514442, 7651417, 24981860, 33961781, 24722188, 24207126, 16189514, 15153109, 16271312, 17316564, 31515488, unassigned1304
Identification Methods two hybrid, far western blotting, affinity chromatography technology, pull down, nuclear magnetic resonance, isothermal titration calorimetry, two hybrid pooling approach, classical fluorescence spectroscopy, surface plasmon resonance, validated two hybrid and 5 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF4E~eIF_4EBP
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0098794 - postsynapse
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 217
Hs

1 120
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Last updated: 15 Jul 2024