Interactor 1: IF4E (P06730)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: EIF4E

Interactor 2: 4ET (Q9NRA8)
Eukaryotic translation initiation factor 4E transporter (4E-T) (eIF4E transporter) (Eukaryotic translation initiation factor 4E nuclear import factor 1)
Gene: EIF4ENIF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 10856257, 29395067, 25416956, 26186194, 28514442, 25923732, 24981860, 33961781, 34133714, 19060904, 24722188, 16189514, 28698298
Identification Methods far western blotting, affinity chromatography technology, proximity labelling technology, two hybrid, two hybrid pooling approach, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, tandem affinity purification and 2 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EIF4E-T~IF4E
Common GO terms GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 217
Hs

1 985
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024