HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: EGR1 (P18146)
Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)
Gene: EGR1

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19374776
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 543
+	Hs
		417909 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZNF16_HUMAN (111-542): 7.59e-125: 382: 15.96
+	Hs
		64134 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZN729_HUMAN (203-541): 1.6e-95: 317: 13.50
+	Hs
		271444 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN624_HUMAN (88-539): 2.95e-158: 474: 13.33
+	Hs
		271254 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZNF16_HUMAN (111-542): 7.59e-125: 382: 15.96
+	Hs
		271392 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN184_HUMAN (14-392): 5.71e-104: 330: 14.25
+	Hs
		64131 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN729_HUMAN (203-541): 1.6e-95: 317: 13.50
+	Hs
		417910 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZNF22_HUMAN (345-442): 8.6e-16: 78.6: 38.78
+	Hs
		271258 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		WT1_HUMAN (327-425): 1.2e-16: 84.3: 44.55
+	Hs
		271255 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZNF22_HUMAN (345-442): 8.6e-16: 78.6: 38.78