Protein: K2C6B
Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6B) (K6B) (Type-II keratin Kb10)

Gene: K2C6B, KRT6B
Organism: Homo sapiens
Interactions: 123
UniProt ID: P04259

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0007398 - ectoderm development
GO:0030280 - structural constituent of skin epidermis
GO:0031424 - keratinization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380443

K1C15
Keratin, type I cytoskeletal 15

4

20

High-throughput

0.911

High

280941

KRT38
Keratin, type I cuticular Ha8

3

20

High-throughput

0.875

High

380480

K1H1
Keratin, type I cuticular Ha1

3

20

High-throughput

0.871

High

380437

K1C19
Keratin, type I cytoskeletal 19

3

20

High-throughput

0.861

High

380441

K1C13
Keratin, type I cytoskeletal 13

3

20

High-throughput

0.845

High

280843

KRT37
Keratin, type I cuticular Ha7

2

20

High-throughput

0.783

High

380474

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.783

High

380488

K1C40
Keratin, type I cytoskeletal 40

2

20

High-throughput

0.783

High

380489

K1C39
Keratin, type I cytoskeletal 39

2

20

High-throughput

0.783

High

380494

K1C28
Keratin, type I cytoskeletal 28

2

20

High-throughput

0.783

High

380495

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

380497

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

380505

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

380515

KIFC3
Kinesin-like protein KIFC3

3

9

High-throughput

0.675

High

49548

A1A4E9
Keratin 13

1

20

High-throughput

0.665

High

280767

KRT36
Keratin, type I cuticular Ha6

1

20

High-throughput

0.621

High

380438

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.621

High

380475

K1H2
Keratin, type I cuticular Ha2

1

20

High-throughput

0.621

High

380483

K1C24
Keratin, type I cytoskeletal 24

1

20

High-throughput

0.621

High

380496

K1C26
Keratin, type I cytoskeletal 26

1

20

High-throughput

0.621

High

380463

UBE3A
Ubiquitin-protein ligase E3A

2

4

Small-scale

0.619

High

380518

TRI54
Tripartite motif-containing protein 54

3

20

High-throughput

0.616

High

380526

TFP11
Tuftelin-interacting protein 11

3

4

High-throughput

0.616

High

380529

GCP4
Gamma-tubulin complex component 4

2

1

High-throughput

0.606

High

154918

NDC80
Kinetochore protein NDC80 homolog

1

20

High-throughput

0.573

High

204271

MS18B
Protein Mis18-beta

2

6

High-throughput

0.553

High

380446

NUP62
Nuclear pore glycoprotein p62

2

5

High-throughput

0.553

High

363680

ALBU
Albumin

1

3

High-throughput

0.536

High

380471

CUL1
Cullin-1

1

20

High-throughput

0.536

High

380472

CUL3
Cullin-3

1

20

High-throughput

0.536

High

380498

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

6

High-throughput

0.536

High

380507

CSN5
COP9 signalosome complex subunit 5

1

16

High-throughput

0.536

High

380508

CUL5
Cullin-5

1

20

High-throughput

0.536

High

345660

MYC
Myc proto-oncogene protein

2

12

High-throughput

0.533

High

380464

GOGA2
Golgin subfamily A member 2

1

7

High-throughput

0.523

High

380467

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

High-throughput

0.494

High

380477

FL2D
Pre-mRNA-splicing regulator WTAP

1

6

High-throughput

0.489

High

380522

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

14

High-throughput

0.489

High

380461

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

6

High-throughput

0.484

High

124717

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

11

Small-scale

0.479

High

133831

DDX3X
ATP-dependent RNA helicase DDX3X

1

5

Small-scale

0.479

High

176338

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

8

High-throughput

0.479

High

197181

SERA
D-3-phosphoglycerate dehydrogenase

1

6

Small-scale

0.479

High

226231

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

255418

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.479

High

282465

RNF8
E3 ubiquitin-protein ligase RNF8

1

14

High-throughput

0.479

High

298039

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

301525

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

380435

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

380439

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

7

High-throughput

0.479

High

380440

CFTR
Cystic fibrosis transmembrane conductance regulator

1

17

High-throughput

0.479

High

380445

CBL
E3 ubiquitin-protein ligase CBL

1

11

High-throughput

0.479

High

380447

IF4A3
Eukaryotic initiation factor 4A-III

1

11

High-throughput

0.479

High

380448

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

380449

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

380451

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.479

High

380458

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

380460

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.479

High

380466

TFCP2
Alpha-globin transcription factor CP2

1

4

High-throughput

0.479

High

380469

TRI26
Tripartite motif-containing protein 26

1

12

Small-scale

0.479

High

380478

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

380479

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

14

High-throughput

0.479

High

380482

MK06
Mitogen-activated protein kinase 6

1

3

High-throughput

0.479

High

380484

LARP7
La-related protein 7

1

11

High-throughput

0.479

High

380487

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

380491

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

380501

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

1

9

Small-scale

0.479

High

380503

PAPD5
Terminal nucleotidyltransferase 4B

1

3

High-throughput

0.479

High

380509

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

7

Small-scale

0.479

High

380510

AP2M1
AP-2 complex subunit mu

1

8

High-throughput

0.479

High

380511

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

380514

NECD
Necdin

1

5

High-throughput

0.479

High

380516

FACD2
Fanconi anemia group D2 protein

1

8

High-throughput

0.479

High

380517

ACE2
Angiotensin-converting enzyme 2

1

6

High-throughput

0.479

High

380520

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

380521

GAN
Gigaxonin

1

5

High-throughput

0.479

High

380523

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

10

High-throughput

0.479

High

380524

ANLN
Anillin

1

11

High-throughput

0.479

High

380527

HDAC6
Histone deacetylase 6

1

13

High-throughput

0.479

High

380528

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

380532

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

9

Small-scale

0.479

High

231955

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.464

High

380456

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

380459

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.458

High

380470

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

380531

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

Small-scale

0.458

High

267361

ECI2
Enoyl-CoA delta isomerase 2

1

2

High-throughput

0.445

High

319691

HERC2
E3 ubiquitin-protein ligase HERC2

1

3

High-throughput

0.445

High

380455

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

380486

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

380499

KIBRA
Protein KIBRA

1

18

High-throughput

0.445

High

380519

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

225459

PCDH7
Protocadherin-7

1

2

High-throughput

0.437

High

302767

HEXI1
Protein HEXIM1

1

18

High-throughput

0.437

High

380436

IGF1R
Insulin-like growth factor 1 receptor

1

3

High-throughput

0.437

High

380442

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.437

High

380444

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

380450

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

380452

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.437

High

380453

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

380454

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

380457

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.437

High

380462

EWS
RNA-binding protein EWS

1

2

High-throughput

0.437

High

380468

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.437

High

380473

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.437

High

380476

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.437

High

380481

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.437

High

380490

PRP8
Pre-mRNA-processing-splicing factor 8

1

8

High-throughput

0.437

High

380492

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

380493

MEPCE
7SK snRNA methylphosphate capping enzyme

1

11

High-throughput

0.437

High

380504

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.437

High

380506

HDAC2
Histone deacetylase 2

1

12

High-throughput

0.437

High

380512

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

380530

AAR2
Protein AAR2 homolog

1

6

High-throughput

0.437

High

380465

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

880

SIM26
Small integral membrane protein 26

1

6

High-throughput

0.407

High

103486

G4U4J3
PAP associated domain containing 5

1

3

High-throughput

0.407

High

146889

AQP7
Aquaporin-7

1

1

Small-scale

0.407

High

380485

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.407

High

380502

MOT11
Monocarboxylate transporter 11

1

3

High-throughput

0.407

High

380513

NEUL4
Neuralized-like protein 4

1

2

High-throughput

0.407

High

380500

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.316

High

380525

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024