HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	20080577, 34079125, 19410544, 16622419, 19410545
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 140
+	Hs
		418161 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		418320 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		418366 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H3C_HUMAN (5-134): 5.15e-52: 162: 47.69
+	Hs
		271347 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		H32_HUMAN (5-134): 1.73e-51: 161: 48.86