HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: PWP1 (Q13610)
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)
Gene: PWP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 501
+	Hs
		418519 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09
+	Mm
		1143203 NPM_MOUSE (1-294): 7.04e-141: 400: 93.54		FBXW7_MOUSE (13-409): 2.33e-57: 204: 12.10
+	Hs
		418535 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88
+	Hs
		418109 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		WDR5_HUMAN (7-223): 2.82e-12: 69.6: 10.08
+	Hs
		418717 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		NLE1_HUMAN (37-167): 4.93e-11: 66.9: 10.69
+	Hs
		271432 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		NLE1_HUMAN (37-167): 4.93e-11: 66.9: 10.69