HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	26496610, 16107701
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006334 - nucleosome assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 126
+	Hs
		418132 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		417977 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		418359 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H2B2C_HUMAN (1-96): 1.25e-43: 143: 91.67
+	Hs
		271297 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21