HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 2229
+	Hs
		418181 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29
+	Hs
		418833 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		418266 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		418503 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		418566 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		418036 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		271390 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37