HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: DHX57 (Q6P158)
Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57)
Gene: DHX57

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 1386
+	Hs
		418410 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DHX29_HUMAN (231-1386): 0: 940: 32.11
+	Hs
		418654 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DHX36_HUMAN (395-1386): 0: 863: 37.98
+	Mm
		250453 NPM_MOUSE (1-294): 7.04e-141: 400: 93.54		DHX9_MOUSE (252-1383): 0: 866: 29.37
+	Hs
		195317 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DHX15_HUMAN (492-1331): 0: 785: 24.70
+	Hs
		418398 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DHX30_HUMAN (473-1361): 0: 709: 30.91
+	Hs
		418445 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DHX37_HUMAN (524-1329): 0: 666: 24.53