HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	31324722, 17110338, 29924966
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 1480
+	Hs
		451184 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		434334 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528953 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529968 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		CFTR_HUMAN (1-1480): 0: 1031: 100.00