HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CACO1 (Q9P1Z2)
Calcium-binding and coiled-coil domain-containing protein 1 (Calphoglin) (Coiled-coil coactivator protein) (Sarcoma antigen NY-SAR-3)
Gene: CALCOCO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 691
+	Hs
		1201957 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		TAXB1_HUMAN (15-680): 1.63e-57: 210: 24.60
+	Hs
		418895 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYH9_HUMAN (201-686): 9.8e-21: 100: 12.25
+	Hs
		451201 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MYH9_HUMAN (201-686): 9.8e-21: 100: 12.25
+	Hs
		434354 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYH9_HUMAN (201-686): 9.8e-21: 100: 12.25
+	Hs
		724765 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MYH9_HUMAN (201-686): 9.8e-21: 100: 12.25
+	Hs
		418974 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		CROCC_HUMAN (67-650): 6.27e-09: 61.6: 9.95
+	Hs
		451267 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CROCC_HUMAN (67-650): 6.27e-09: 61.6: 9.95
+	Rn
		1186812 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKB_RAT (78-654): 1.52e-32: 137: 14.79
+	Dm
		404216 TPM2_DROME (2-284): 6.48e-36: 131: 47.70		MYSA_DROME (150-431): 2.29e-10: 66.5: 14.69
+	Hs
		1137917 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MRCKA_HUMAN (100-672): 4.1e-26: 117: 14.89
+	Hs
		110796 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MYH9_HUMAN (201-686): 9.8e-21: 100: 12.25
+	Rn
		222476 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKA_RAT (308-676): 3.17e-15: 82: 10.40