HitPredict

Interactor 1: ITAV (P06756)
Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]
Gene: ITGAV

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0008284 - positive regulation of cell population proliferation GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1048 Hs			1 191
+	Hs
		419189 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		419149 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		419185 ITAV_HUMAN (28-1048): 0: 1193: 100.00		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		419186 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		419135 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		419184 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		419150 ITAV_HUMAN (28-1048): 0: 1193: 100.00		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		443068 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		443071 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		443028 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		443060 ITA5_HUMAN (28-1044): 0: 1041: 45.44		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		443063 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436126 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		443059 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		443030 ITA5_HUMAN (28-1044): 0: 1041: 45.44		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		545210 ITA6_HUMAN (9-1040): 0: 904: 25.48		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		613232 ITA6_HUMAN (9-1040): 0: 904: 25.48		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		436159 ITA6_HUMAN (9-1040): 0: 904: 25.48		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		613231 ITA6_HUMAN (9-1040): 0: 904: 25.48		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564413 ITA6_HUMAN (9-1040): 0: 904: 25.48		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84