Interactor 1: RHO1 (P06780)
GTP-binding protein RHO1 (EC 3.6.5.2) (Rho-type GTPase 1)
Gene: RHO1

Interactor 2: KPC1 (P24583)
Protein kinase C-like 1 (PKC 1) (EC 2.7.11.13)
Gene: PKC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 11994162, 8846785, 8621575, 19564916, 11489916, 28065784, 23878277, 18552287, 18256282, 22727045, 20171953
Identification Methods two hybrid, coimmunoprecipitation, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Ras, HR1~Ras, Pkinase~Ras
Common GO terms GO:0005886 - plasma membrane
GO:0005935 - cellular bud neck
GO:0007165 - signal transduction
GO:0009272 - fungal-type cell wall biogenesis
GO:0032186 - cellular bud neck septin ring organization
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 209
Sc

1 1151
+ Hs
+ Sp
+ Sp
+ Hs
+ Sp
+ Sp
+ Sp
+ Hs
+ Hs
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024