HitPredict

Interactor 1: RHO2 (P06781)
GTP-binding protein RHO2 (EC 3.6.5.2)
Gene: RHO2

Interactor 2: LRG1 (P35688)
Rho-GTPase-activating protein LRG1 (LIM-RhoGAP protein 1)
Gene: LRG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11591390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Sc			1 1017
+	Sc
		419681 RHO1_YEAST (1-185): 7.08e-89: 261: 52.88		LRG1_YEAST (1-1017): 0: 856: 100.00
+	Ce
		93901 RHO1_CAEEL (5-191): 9.61e-90: 262: 50.53		F0IWT2_CAEEL (371-944): 2.2e-81: 293: 15.73
+	Hs
		915815 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG12_HUMAN (393-935): 6.2e-79: 277: 14.94
+	Hs
		915958 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RGAP1_HUMAN (446-1016): 3.44e-75: 262: 14.77
+	Hs
		915753 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG17_HUMAN (504-1017): 6.49e-73: 261: 15.78
+	Hs
		915737 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG21_HUMAN (548-1009): 5.36e-70: 258: 15.67
+	Hs
		63072 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG42_HUMAN (442-986): 1.45e-77: 274: 12.57
+	Hs
		915827 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG18_HUMAN (487-1005): 1.74e-70: 249: 17.61
+	Hs
		915721 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG29_HUMAN (486-1017): 4.77e-67: 248: 13.48
+	Hs
		915641 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		ABR_HUMAN (433-944): 2.17e-68: 247: 15.50
+	Hs
		64686 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG32_HUMAN (690-1013): 3.52e-64: 240: 17.68
+	Hs
		892584 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RGAP1_HUMAN (446-1016): 3.44e-75: 262: 14.77
+	Hs
		892420 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG21_HUMAN (548-1009): 5.36e-70: 258: 15.67
+	Sc
		419747 RHO2_YEAST (1-192): 8.02e-81: 239: 100.00		RGD1_YEAST (466-929): 2.61e-67: 240: 16.84
+	Hs
		64679 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG32_HUMAN (690-1013): 3.52e-64: 240: 17.68
+	Hs
		915629 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG01_HUMAN (726-935): 8.52e-52: 190: 28.44
+	Hs
		892334 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG01_HUMAN (726-935): 8.52e-52: 190: 28.44
+	Mm
		925791 RAC1_MOUSE (8-192): 5.1e-79: 235: 43.92		RHG01_MOUSE (726-935): 4.48e-52: 191: 28.44
+	Gg
		823526 Q6LC82_CHICK (8-192): 5.1e-79: 235: 43.92		PAXI_CHICK (23-219): 4.55e-45: 173: 18.75
+	Hs
		915764 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHGBA_HUMAN (723-960): 3.81e-13: 75.9: 27.73