HitPredict

Interactor 1: RHO2 (P06781)
GTP-binding protein RHO2 (EC 3.6.5.2)
Gene: RHO2

Interactor 2: RGD1 (P38339)
RHO GTPase-activating protein RGD1 (RhoGAP) (Related GAP domain protein 1)
Gene: RGD1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	10526184
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Sc			1 666
+	Hs
		253333 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		SRGP2_HUMAN (33-664): 2.84e-112: 364: 12.79
+	Hs
		915721 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG29_HUMAN (28-665): 2.03e-100: 335: 18.13
+	Hs
		63072 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG42_HUMAN (81-664): 7.07e-104: 337: 14.00
+	Hs
		916006 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG35_HUMAN (98-663): 6.13e-87: 299: 13.97
+	Hs
		915815 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG12_HUMAN (145-664): 1.23e-85: 288: 17.62
+	Hs
		915958 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RGAP1_HUMAN (105-666): 1.29e-84: 280: 17.90
+	Hs
		892620 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG35_HUMAN (98-663): 6.13e-87: 299: 13.97
+	Hs
		506564 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		BCR_HUMAN (77-643): 3.46e-76: 267: 15.71
+	Hs
		915737 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG21_HUMAN (169-666): 4e-75: 265: 18.11
+	Hs
		915643 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RHG05_HUMAN (250-663): 5.71e-73: 259: 15.79
+	Hs
		892584 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RGAP1_HUMAN (105-666): 1.29e-84: 280: 17.90
+	Mm
		925798 RAC1_MOUSE (8-192): 5.1e-79: 235: 43.92		BCR_MOUSE (56-643): 3.63e-77: 270: 15.77
+	Hs
		892420 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG21_HUMAN (169-666): 4e-75: 265: 18.11
+	Hs
		892343 RAC3_HUMAN (9-178): 5.33e-80: 238: 47.40		RHG05_HUMAN (250-663): 5.71e-73: 259: 15.79
+	Ce
		88291 RHO1_CAEEL (5-191): 9.61e-90: 262: 50.53		D3YT91_CAEEL (181-663): 9.13e-68: 232: 17.84
+	Hs
		915641 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		ABR_HUMAN (462-663): 1.38e-62: 225: 29.91
+	Mm
		925793 RAC1_MOUSE (8-192): 5.1e-79: 235: 43.92		ABR_MOUSE (462-663): 1.63e-62: 225: 30.37
+	Hs
		915692 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		RBP1_HUMAN (470-638): 7.78e-14: 77: 28.90
+	Hs
		70668 RHOB_HUMAN (5-192): 6.85e-89: 260: 51.55		MYO9A_HUMAN (468-634): 3.36e-13: 75.5: 29.34
+	Sc
		419749 RHO2_YEAST (1-192): 8.02e-81: 239: 100.00		BEM2_YEAST (468-657): 4.19e-12: 72: 28.06