HitPredict

Interactor 1: CRF (P06850)
Corticoliberin (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone)
Gene: CRH

Interactor 2: CRFR1 (P34998)
Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)
Gene: CRHR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.926

Property	Details
Experiments	10598591, 9423932, 19124613, 18801728, 20966082
Identification Methods	pull down, unspecified method, x-ray crystallography, luminiscence technology, amplified luminescent proximity homogeneous assay
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	7tm_2~CRF, CRF~HRM
Common GO terms	GO:0007565 - female pregnancy GO:0007567 - parturition GO:0030325 - adrenal gland development
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 415
+	Hs
		420643 CRF_HUMAN (1-196): 2.55e-111: 317: 100.00		CRFR2_HUMAN (34-415): 1.26e-117: 350: 72.85