HitPredict

Interactor 1: KLK1 (P06870)
Kallikrein-1 (EC 3.4.21.35) (Kidney/pancreas/salivary gland kallikrein) (Tissue kallikrein)
Gene: KLK1

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 262 Hs			1 444
+	Hs
		428722 TRY2_HUMAN (4-262): 2.81e-110: 319: 40.15		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		1037427 KLK11_HUMAN (22-261): 6.14e-106: 309: 42.08		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		1037334 KLK6_HUMAN (1-260): 1.36e-100: 295: 36.54		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		428515 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		1037451 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		934035 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		1114231 KLK15_HUMAN (15-261): 8.5e-98: 288: 36.97		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		1046624 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Hs
		1312839 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		381331 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		428427 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		1037390 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		933971 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		1114269 KLK5_HUMAN (8-262): 1.35e-93: 279: 37.35		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		1046575 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Hs
		1312808 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		381216 PRSS8_HUMAN (4-260): 1.06e-89: 270: 30.99		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		381298 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		1114233 TMPS5_HUMAN (13-261): 6.66e-88: 270: 33.85		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		621370 CMA1_HUMAN (25-261): 1.72e-37: 134: 35.63		TBB8_HUMAN (1-427): 0: 708: 100.00