Protein: AT2C1
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) (SPCA1)

Gene: AT2C1, ATP2C1
Organism: Homo sapiens
Interactions: 130
UniProt ID: P98194

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005388 - P-type calcium transporter activity
GO:0005509 - calcium ion binding
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1023406

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

5

High-throughput

0.789

High

1023349

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.691

High

1023362

TEFF1
Tomoregulin-1

3

1

High-throughput

0.667

High

1023346

OGFD3
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3

3

0

High-throughput

0.638

High

1023354

TM11B
Transmembrane protease serine 11B

2

7

High-throughput

0.611

High

1010019

DLK1
Protein delta homolog 1

2

5

High-throughput

0.601

High

1023382

OPALI
Opalin

2

3

High-throughput

0.601

High

1023393

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.601

High

936032

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.541

High

1023396

GPR35
G-protein coupled receptor 35

1

20

High-throughput

0.541

High

125013

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

165929

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.536

High

182508

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.536

High

292342

RA51D
DNA repair protein RAD51 homolog 4

1

1

High-throughput

0.536

High

320444

TM63A
Mechanosensitive cation channel TMEM63A

1

2

High-throughput

0.536

High

349405

TSN15
Tetraspanin-15

1

10

High-throughput

0.536

High

351888

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.536

High

564909

ICAM2
Intercellular adhesion molecule 2

1

3

High-throughput

0.536

High

638181

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.536

High

711549

NK3R
Neuromedin-K receptor

1

14

High-throughput

0.536

High

820552

GPV
Platelet glycoprotein V

1

10

High-throughput

0.536

High

878019

AGRE5
Adhesion G protein-coupled receptor E5

1

1

High-throughput

0.536

High

888851

TMEDA
Transmembrane emp24 domain-containing protein 10

1

5

High-throughput

0.536

High

900774

RAB5C
Ras-related protein Rab-5C

1

8

High-throughput

0.536

High

904230

P2RX1
P2X purinoceptor 1

1

4

High-throughput

0.536

High

907008

CCR6
C-C chemokine receptor type 6

1

20

High-throughput

0.536

High

1023330

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

1

High-throughput

0.536

High

1023332

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

8

High-throughput

0.536

High

1023335

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

1023338

SGCA
Alpha-sarcoglycan

1

1

High-throughput

0.536

High

1023342

AGK
Acylglycerol kinase, mitochondrial

1

1

High-throughput

0.536

High

1023345

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.536

High

1023351

SO4C1
Solute carrier organic anion transporter family member 4C1

1

1

High-throughput

0.536

High

1023355

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

20

High-throughput

0.536

High

1023366

LRC25
Leucine-rich repeat-containing protein 25

1

1

High-throughput

0.536

High

1023371

F174A
Membrane protein FAM174A

1

3

High-throughput

0.536

High

1023373

NEUFC
Neuferricin

1

4

High-throughput

0.536

High

1023377

YIPF5
Protein YIPF5

1

3

High-throughput

0.536

High

1023394

GORS2
Golgi reassembly-stacking protein 2

1

1

High-throughput

0.536

High

1023395

LPAR2
Lysophosphatidic acid receptor 2

1

20

High-throughput

0.536

High

1023397

TMM9B
Transmembrane protein 9B

1

2

High-throughput

0.536

High

1023402

P2RX2
P2X purinoceptor 2

1

4

High-throughput

0.536

High

1023404

CLC2D
C-type lectin domain family 2 member D

1

7

High-throughput

0.536

High

1023408

GOT1B
Vesicle transport protein GOT1B

1

2

High-throughput

0.536

High

1023409

GPR45
Probable G-protein coupled receptor 45

1

18

High-throughput

0.536

High

190343

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

1023375

BSND
Barttin

1

0

High-throughput

0.513

High

1023372

HUMMR
Protein MGARP

1

1

High-throughput

0.489

High

178246

NPC1
NPC intracellular cholesterol transporter 1

1

5

High-throughput

0.479

High

218065

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

293564

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.479

High

411741

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

611084

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

7

High-throughput

0.479

High

627518

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

11

High-throughput

0.479

High

961953

RHOA
Transforming protein RhoA

1

13

High-throughput

0.479

High

1023336

EMC2
ER membrane protein complex subunit 2

1

3

High-throughput

0.479

High

1023344

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1023348

LMBRL
Protein LMBR1L

1

4

High-throughput

0.479

High

1023357

GOLI
E3 ubiquitin-protein ligase RNF130

1

6

High-throughput

0.479

High

1023363

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.479

High

1023367

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.479

High

1023368

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.479

High

1023369

RN149
E3 ubiquitin-protein ligase RNF149

1

6

High-throughput

0.479

High

1023380

FAF2
FAS-associated factor 2

1

5

High-throughput

0.479

High

1023389

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.479

High

1023390

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1023400

ELOV5
Very long chain fatty acid elongase 5

1

3

High-throughput

0.479

High

1023401

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1023405

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.479

High

1023364

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

139205

UPK2
Uroplakin-2

1

2

High-throughput

0.445

High

189980

MOT7
Monocarboxylate transporter 7

1

12

High-throughput

0.445

High

190215

MOT4
Monocarboxylate transporter 4

1

11

High-throughput

0.445

High

211129

CTR4
Cationic amino acid transporter 4

1

4

High-throughput

0.445

High

254968

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.445

High

303227

S22A5
Organic cation/carnitine transporter 2

1

7

High-throughput

0.445

High

351217

MOT3
Monocarboxylate transporter 3

1

11

High-throughput

0.445

High

468266

HS90B
Heat shock protein HSP 90-beta

1

6

High-throughput

0.445

High

652183

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

9

High-throughput

0.445

High

669314

ACKR3
Atypical chemokine receptor 3

1

20

High-throughput

0.445

High

704003

5HT1E
5-hydroxytryptamine receptor 1E

1

5

High-throughput

0.445

High

722442

CTR1
High affinity cationic amino acid transporter 1

1

4

High-throughput

0.445

High

869582

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

5

High-throughput

0.445

High

870222

S6A12
Sodium- and chloride-dependent betaine transporter

1

5

High-throughput

0.445

High

870352

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

5

High-throughput

0.445

High

886046

CXCR3
C-X-C chemokine receptor type 3

1

20

High-throughput

0.445

High

1023333

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

20

High-throughput

0.445

High

1023334

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1023337

S15A2
Solute carrier family 15 member 2

1

6

High-throughput

0.445

High

1023340

S35G1
Solute carrier family 35 member G1

1

8

High-throughput

0.445

High

1023347

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

8

High-throughput

0.445

High

1023353

RIC3
Protein RIC-3

1

2

High-throughput

0.445

High

1023359

S35F2
Solute carrier family 35 member F2

1

7

High-throughput

0.445

High

1023361

S35F3
Solute carrier family 35 member F3

1

1

High-throughput

0.445

High

1023370

ZNT7
Zinc transporter 7

1

4

High-throughput

0.445

High

1023374

S35F5
Solute carrier family 35 member F5

1

6

High-throughput

0.445

High

1023376

LPAR1
Lysophosphatidic acid receptor 1

1

20

High-throughput

0.445

High

1023381

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

6

High-throughput

0.445

High

1023384

S1PR3
Sphingosine 1-phosphate receptor 3

1

20

High-throughput

0.445

High

1023385

S22A4
Solute carrier family 22 member 4

1

7

High-throughput

0.445

High

1023387

UN93B
Protein unc-93 homolog B1

1

3

High-throughput

0.445

High

1023388

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

5

High-throughput

0.445

High

1023407

S27A5
Long-chain fatty acid transport protein 5

1

4

High-throughput

0.445

High

174502

TRI66
Tripartite motif-containing protein 66

1

4

High-throughput

0.437

High

227503

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.437

High

830566

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

1004450

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

1023328

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.437

High

1023339

DUS7
Dual specificity protein phosphatase 7

1

1

High-throughput

0.437

High

1023350

BAKOR
Beclin 1-associated autophagy-related key regulator

1

2

High-throughput

0.437

High

1023352

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1023356

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1023379

OTUL
Ubiquitin thioesterase otulin

1

2

Small-scale

0.437

High

1023383

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.437

High

1023386

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.437

High

1023392

TM231
Transmembrane protein 231

1

1

High-throughput

0.437

High

1023399

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

923412

SC5A3
Sodium/myo-inositol cotransporter

1

0

High-throughput

0.426

High

1023329

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

1023331

NPT2A
Sodium-dependent phosphate transport protein 2A

1

0

High-throughput

0.426

High

1023365

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.426

High

1023341

ATG2A
Autophagy-related protein 2 homolog A

1

2

Small-scale

0.407

High

1023343

S35F1
Solute carrier family 35 member F1

1

11

High-throughput

0.407

High

1023358

S22A9
Organic anion transporter 7

1

7

High-throughput

0.407

High

1023360

S15A3
Solute carrier family 15 member 3

1

6

High-throughput

0.407

High

1023378

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.407

High

1023403

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

Small-scale

0.251

Low

869018

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.249

Low

1023398

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.249

Low

1023391

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025