HitPredict

Interactor 1: SYV (P07118)
Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)
Gene: valS

Interactor 2: EFTU1 (P0CE47)
Elongation factor Tu 1 (EF-Tu 1) (Bacteriophage Q beta RNA-directed RNA polymerase subunit III) (P-43)
Gene: tufA

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19402753, 15690043
Identification Methods	tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 951 Ec			1 394
+	Ec
		421430 SYV_ECOLI (1-951): 0: 989: 100.00		EFTU2_ECOLI (1-394): 9.26e-158: 451: 99.75
+	Hs
		643842 SYVC_HUMAN (1-951): 0: 928: 38.67		EF1A1_HUMAN (6-392): 2.55e-133: 391: 27.03
+	Hs
		643849 SYVC_HUMAN (1-951): 0: 928: 38.67		EF1A2_HUMAN (6-392): 4.94e-133: 390: 27.48
+	Hs
		827418 SYVM_HUMAN (1-944): 0: 884: 33.84		EFTU_HUMAN (2-394): 4.36e-147: 426: 55.44
+	Ec
		343741 SYI_ECOLI (2-880): 0: 660: 17.94		EFTU2_ECOLI (1-394): 9.26e-158: 451: 99.75
+	Ec
		343740 SYI_ECOLI (2-880): 0: 660: 17.94		EFTU1_ECOLI (1-394): 4.18e-157: 449: 100.00
+	Hs
		827621 SYIM_HUMAN (8-892): 0: 672: 18.60		EFTU_HUMAN (2-394): 4.36e-147: 426: 55.44
+	Sc
		367632 SYIC_YEAST (5-947): 0: 701: 17.87		EF1A_YEAST (6-392): 1.51e-131: 386: 27.60
+	Hs
		932901 SYLC_HUMAN (7-943): 0: 635: 15.16		EF1A1_HUMAN (6-392): 2.55e-133: 391: 27.03
+	Mt
		191411 SYL_METTH (9-821): 6.55e-170: 521: 22.37		EF1A_METTH (8-388): 6.94e-53: 182: 34.68
+	Tk
		1126799 SYL_THEKO (6-918): 3.7e-137: 436: 20.41		EF1A_THEKO (8-392): 1.04e-61: 206: 36.32