HitPredict

Interactor 1: B2MG (P07151)
Beta-2-microglobulin
Gene: B2m

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~fn3, C1-set~Furin-like, C1-set~Recep_L_domain
Common GO terms	GO:0005198 - structural molecule activity GO:0009897 - external side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 119 Rn			1 1383
+	Rn
		544828 Q31255_RAT (2-117): 4.51e-45: 151: 22.22		INSR_RAT (1-1383): 0: 1575: 100.00
+	Hs
		382263 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		INSR_HUMAN (27-1383): 0: 1527: 95.43
+	Hs
		382269 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		IGF1R_HUMAN (13-1381): 0: 1302: 55.77
+	Hs
		435507 HLAC_HUMAN (2-117): 5.35e-48: 158: 21.37		IGF1R_HUMAN (13-1381): 0: 1302: 55.77
+	Hs
		588758 DPA1_HUMAN (18-116): 1.8e-45: 149: 31.00		EPHA4_HUMAN (662-1328): 0: 570: 24.19
+	Hs
		588774 DPA1_HUMAN (18-116): 1.8e-45: 149: 31.00		EPHA7_HUMAN (664-1321): 0: 568: 22.55
+	Hs
		533134 HLAE_HUMAN (3-117): 6.33e-44: 148: 23.28		EPHB4_HUMAN (662-1321): 3.03e-170: 536: 24.96
+	Hs
		382560 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57
+	Hs
		169162 HLAC_HUMAN (2-117): 5.35e-48: 158: 21.37		MUSK_HUMAN (1018-1292): 3.32e-69: 253: 42.22
+	Hs
		169158 HLAB_HUMAN (2-117): 3.45e-46: 153: 22.22		MUSK_HUMAN (1018-1292): 3.32e-69: 253: 42.22
+	Hs
		382259 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		382433 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		488237 HLAC_HUMAN (2-117): 5.35e-48: 158: 21.37		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		673955 HLAF_HUMAN (2-116): 1.05e-47: 157: 21.55		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		382307 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		488123 HLAC_HUMAN (2-117): 5.35e-48: 158: 21.37		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		337747 HLAA_HUMAN (2-116): 7.51e-49: 160: 21.55		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		337829 HLAC_HUMAN (2-117): 5.35e-48: 158: 21.37		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		337728 HLAH_HUMAN (2-117): 8.85e-47: 155: 22.22		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		588748 DPA1_HUMAN (18-116): 1.8e-45: 149: 31.00		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70