Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL
Interactor 2: NFM (P07197)
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.962 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 32296183, 34079125, 33961781, 34349018, 35235311, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, proximity labelling technology, cross-linking study, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Filament~Filament |
| Common GO terms | GO:0005200 - structural constituent of cytoskeleton GO:0005737 - cytoplasm GO:0005882 - intermediate filament GO:0005883 - neurofilament GO:0030424 - axon and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
