HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019904 - protein domain specific binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 862
+	Hs
		409081 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00
+	Hs
		148291 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		408987 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		MYH1_HUMAN (1-681): 1.56e-26: 119: 9.77
+	Hs
		148869 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		148307 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		422356 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		MYH10_HUMAN (7-484): 2.28e-14: 79.7: 11.09
+	Hs
		422355 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		MYH9_HUMAN (486-859): 1.31e-13: 77.4: 12.90
+	Hs
		148292 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		148372 DESM_HUMAN (69-402): 4.31e-72: 239: 53.89		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		148347 GFAP_HUMAN (66-401): 1.36e-70: 234: 48.21		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		148487 PERI_HUMAN (9-401): 1.77e-69: 232: 48.12		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86