HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: RSPRY (Q96DX4)
RING finger and SPRY domain-containing protein 1
Gene: RSPRY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 576
+	Hs
		1081746 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		443716 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		422438 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		535517 GFAP_HUMAN (66-401): 1.36e-70: 234: 48.21		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Mm
		93446 AINX_MOUSE (65-401): 8.37e-89: 283: 56.47		RYR2_MOUSE (263-493): 7.48e-16: 83.6: 18.99