Interactor 1: TGFB1 (P07200)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: TGFB1 (P07200)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Species: Sus scrofa

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 21677751
Identification Methods x-ray crystallography, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide
Common GO terms GO:0001837 - epithelial to mesenchymal transition
GO:0001933 - negative regulation of protein phosphorylation
GO:0002062 - chondrocyte differentiation
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0003823 - antigen binding
and 72 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 390
Ss

1 390
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024