HitPredict

Interactor 1: SYTM (P07236)
Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)
Gene: MST1

Interactor 2: SYTM (P07236)
Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS)
Gene: MST1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	26704982, 22343532
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	HGTP_anticodon~HGTP_anticodon, HGTP_anticodon~tRNA-synt_2b, tRNA-synt_2b~tRNA-synt_2b
Common GO terms	GO:0004829 - threonine-tRNA ligase activity GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0070159 - mitochondrial threonyl-tRNA aminoacylation
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 462 Sc			1 462
+	Hs
		58217 SYTC_HUMAN (2-459): 1.14e-178: 519: 40.47		SYTC2_HUMAN (1-461): 7.27e-173: 507: 39.15
+	Hs
		58205 B2RDX5_HUMAN (2-459): 9.12e-179: 518: 40.47		SYTC2_HUMAN (1-461): 7.27e-173: 507: 39.15
+	Sc
		388920 SYTC_YEAST (1-462): 8.22e-170: 496: 38.32		SYTC_YEAST (1-462): 8.22e-170: 496: 38.32
+	Hs
		58247 SYTC2_HUMAN (1-461): 7.27e-173: 507: 39.15		SYTM_HUMAN (12-461): 2.8e-162: 477: 38.85
+	Ec
		463566 SYT_ECOLI (1-461): 3.37e-159: 466: 34.62		SYT_ECOLI (1-461): 3.37e-159: 466: 34.62
+	Sc
		388977 SYTC_YEAST (1-462): 8.22e-170: 496: 38.32		YHI0_YEAST (19-462): 2.1e-125: 381: 13.79
+	Hs
		430843 SYEP_HUMAN (13-462): 3.71e-128: 406: 14.35		SYEP_HUMAN (13-462): 3.71e-128: 406: 14.35
+	Pf
		1211801 SYP_PLAF7 (11-462): 5.85e-116: 359: 16.70		SYP_PLAF7 (11-462): 5.85e-116: 359: 16.70
+	Ec
		561957 SYP_ECOLI (271-459): 1.6e-32: 131: 21.54		SYP_ECOLI (271-459): 1.6e-32: 131: 21.54
+	Hp
		879665 SYP_HELPY (293-460): 4.91e-12: 69.8: 15.03		SYP_HELPY (293-460): 4.91e-12: 69.8: 15.03