HitPredict

Interactor 1: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Interactor 2: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 375
+	Hs
		423304 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		671939 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00
+	Hs
		671877 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		423359 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DJC18_HUMAN (51-375): 5.94e-85: 263: 39.71
+	Hs
		423386 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27
+	Hs
		671925 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJC18_HUMAN (51-375): 5.94e-85: 263: 39.71
+	Hs
		423379 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DNJB9_HUMAN (85-247): 2.18e-42: 149: 31.29
+	Hs
		423380 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		636249 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DNJB1_HUMAN (109-251): 2.52e-42: 152: 37.42
+	Hs
		671947 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DNJB9_HUMAN (85-247): 2.18e-42: 149: 31.29
+	Hs
		532000 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		DJB12_HUMAN (1-375): 1.18e-140: 406: 100.00
+	Hs
		531914 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		DJB14_HUMAN (1-375): 1.97e-123: 362: 51.32
+	Hs
		671948 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		531986 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		DJC18_HUMAN (51-375): 5.94e-85: 263: 39.71
+	Hs
		532015 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		SEC63_HUMAN (87-373): 4.84e-51: 183: 19.27
+	Rn
		956846 DJC10_RAT (265-491): 9.68e-22: 101: 17.62		DNJB9_RAT (102-239): 6.88e-46: 158: 33.81
+	Hs
		532010 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		DNJB9_HUMAN (85-247): 2.18e-42: 149: 31.29
+	Hs
		532011 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66
+	Rn
		1115513 DJC10_RAT (265-491): 9.68e-22: 101: 17.62		DJB11_RAT (109-189): 1.2e-18: 88.2: 53.66
+	Hs
		1220492 DJC10_HUMAN (248-481): 6.3e-22: 101: 18.38		DJB11_HUMAN (109-189): 1.2e-18: 88.2: 53.66