Protein: MIER1
Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1)

Gene: MIER1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q8N108

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1109884

HDAC1
Histone deacetylase 1

9

20

Small-scale

0.978

High

1322540

HDAC2
Histone deacetylase 2

6

20

Small-scale

0.943

High

1322549

CDYL
Chromodomain Y-like protein

4

2

High-throughput

0.697

High

1322542

H2B1A
Histone H2B type 1-A

4

13

High-throughput

0.691

High

591728

H2AX
Histone H2AX

3

18

High-throughput

0.675

High

502051

H2AZ
Histone H2A.Z

3

20

High-throughput

0.667

High

1322541

CBP
CREB-binding protein

1

20

Small-scale

0.647

High

1322543

EHMT2
Histone-lysine N-methyltransferase EHMT2

3

14

Small-scale

0.643

High

50027

F170A
Protein FAM170A

3

0

High-throughput

0.638

High

1067501

EP300
Histone acetyltransferase p300

1

20

High-throughput

0.618

High

872520

SOX2
Transcription factor SOX-2

2

20

High-throughput

0.611

High

1322538

DOK4
Docking protein 4

2

4

High-throughput

0.611

High

1244433

CP087
UPF0547 protein C16orf87

3

2

High-throughput

0.604

High

1133261

ARI5B
AT-rich interactive domain-containing protein 5B

2

7

High-throughput

0.601

High

980918

H2B1C
Histone H2B type 1-C/E/F/G/I

2

13

High-throughput

0.584

High

1277265

MIER3
Mesoderm induction early response protein 3

1

12

High-throughput

0.575

High

1200533

CYBR1
Plasma membrane ascorbate-dependent reductase CYBRD1

2

1

High-throughput

0.574

High

238560

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.536

High

344965

WIZ
Protein Wiz

1

4

High-throughput

0.536

High

419079

H2A1B
Histone H2A type 1-B/E

1

15

High-throughput

0.536

High

502430

H2A1
Histone H2A type 1

1

15

High-throughput

0.536

High

885838

KC1E
Casein kinase I isoform epsilon

1

4

High-throughput

0.536

High

1091072

FOXF2
Forkhead box protein F2

1

11

High-throughput

0.536

High

1099726

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

3

High-throughput

0.536

High

1162830

H2A2C
Histone H2A type 2-C

1

15

High-throughput

0.536

High

1232694

H2A2A
Histone H2A type 2-A

1

15

High-throughput

0.536

High

1322533

H2B3B
Histone H2B type 3-B

1

13

High-throughput

0.536

High

1322544

H2AJ
Histone H2A.J

1

15

High-throughput

0.536

High

943390

H2BFS
Histone H2B type F-S

1

13

High-throughput

0.515

High

582876

EZRI
Ezrin

1

3

High-throughput

0.515

High

1096092

TADBP
TAR DNA-binding protein 43

1

3

High-throughput

0.515

High

1142476

RAGE
Advanced glycosylation end product-specific receptor

1

1

High-throughput

0.515

High

1157465

PKN1
Serine/threonine-protein kinase N1

1

2

High-throughput

0.515

High

1031922

NC2B
Protein Dr1

1

0

High-throughput

0.513

High

1106605

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.513

High

1259001

CENPU
Centromere protein U

1

0

High-throughput

0.513

High

1322550

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.513

High

422557

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

667365

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.493

High

143112

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

320344

PHF14
PHD finger protein 14

1

5

High-throughput

0.479

High

363554

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

474119

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

979969

H4
Histone H4

1

5

High-throughput

0.479

High

998531

H31
Histone H3.1

1

20

High-throughput

0.479

High

1087863

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1133528

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1145269

RNPS1
RNA-binding protein with serine-rich domain 1

1

3

High-throughput

0.479

High

1322536

ZBT38
Zinc finger and BTB domain-containing protein 38

1

2

Small-scale

0.479

High

1322545

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1322546

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

1322551

CDY2
Testis-specific chromodomain protein Y 2

1

2

High-throughput

0.479

High

728794

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.470

High

187133

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.458

High

1187974

GON4L
GON-4-like protein

1

0

High-throughput

0.458

High

1322534

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

274354

SIN3B
Paired amphipathic helix protein Sin3b

1

8

High-throughput

0.445

High

442765

RB
Retinoblastoma-associated protein

1

1

High-throughput

0.445

High

1322537

BAHD1
Bromo adjacent homology domain-containing 1 protein

1

1

High-throughput

0.445

High

374046

RASN
GTPase NRas

1

1

High-throughput

0.437

High

1322547

RM39
Large ribosomal subunit protein mL39

1

1

High-throughput

0.437

High

617449

DNLI1
DNA ligase 1

1

2

Small-scale

0.408

High

1161937

H31T
Histone H3.1t

1

20

High-throughput

0.408

High

1322548

KLH13
Kelch-like protein 13

1

2

High-throughput

0.407

High

1322539

TM171
Transmembrane protein 171

1

0

High-throughput

0.299

High

1322535

SYT2
Synaptotagmin-2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025