HitPredict

Interactor 1: C1TC (P07245)
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
Gene: ADE3

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31399574, 37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 946 Sc			1 705
+	Hs
		437841 C1TC_HUMAN (3-946): 0: 1510: 57.49		HS90B_HUMAN (5-705): 0: 1022: 61.15
+	Hs
		431474 C1TC_HUMAN (3-946): 0: 1510: 57.49		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Sc
		450385 C1TM_YEAST (4-946): 0: 1446: 71.10		HSC82_YEAST (1-705): 0: 977: 100.00
+	Sc
		365570 C1TC_YEAST (1-946): 0: 1447: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Sc
		365613 C1TM_YEAST (4-946): 0: 1446: 71.10		HSP82_YEAST (1-705): 0: 968: 95.63
+	Sc
		544265 MTD1_YEAST (3-298): 2.88e-82: 270: 23.51		HSC82_YEAST (1-705): 0: 977: 100.00
+	Sc
		366753 MTD1_YEAST (3-298): 2.88e-82: 270: 23.51		HSP82_YEAST (1-705): 0: 968: 95.63