Interactor 1: IF4E (P07260)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: CDC33

Interactor 2: IF4F1 (P39935)
Eukaryotic initiation factor 4F subunit p150 (eIF-4F p150) (eIF4F p150) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 1) (eIF4G1) (mRNA cap-binding protein complex subunit p150)
Gene: TIF4631

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 9707439, 8336723, 9372919, 12861028, 10480875, 11805826, 16429126, 25826658, 30053226, 29987188, 25973932, 30065356, 37700444, 37070186, 23226381, 16554755, 25013175, 37968396, 21139564, 23184954 and 4 others

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Identification Methods affinity chromatography technology, biochemical, coimmunoprecipitation, filter binding, surface plasmon resonance, tandem affinity purification, pull down, two hybrid, far western blotting, anti tag coimmunoprecipitation and 2 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF4E~eIF_4G1
Common GO terms GO:0003743 - translation initiation factor activity
GO:0005737 - cytoplasm
GO:0005840 - ribosome
GO:0006413 - translational initiation
GO:0006446 - regulation of translational initiation
and 3 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 213
Sc

1 952
+ Sc
+ Dm
+ Dm
+ Dm
+ Dm
+ Mm
+ Hs
+ Mm
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ At
+ At
+ Ce
+ At
+ Hs

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Last updated: 15 Jul 2024