Interactor 1: IF4E (P07260)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)
Gene: CDC33

Interactor 2: IF4F2 (P39936)
Eukaryotic initiation factor 4F subunit p130 (eIF-4F p130) (eIF4F p130) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 2) (eIF4G2) (mRNA cap-binding protein complex subunit p130)
Gene: TIF4632

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 9372919, 11805826, 16554755, 16429126, 37968396, 23184954, 30065356, 9003792
Identification Methods coimmunoprecipitation, affinity chromatography technology, filter binding, tandem affinity purification, biochemical, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IF4E~eIF_4G1
Common GO terms GO:0003743 - translation initiation factor activity
GO:0005840 - ribosome
GO:0006413 - translational initiation
GO:0006446 - regulation of translational initiation
GO:0010494 - cytoplasmic stress granule
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 213
Sc

1 914
+ Sc
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ At
+ Ce
+ Dm
+ At
+ At
+ Mm

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Last updated: 15 Jul 2024