Protein: SOX9
Transcription factor SOX-9

Gene: SOX9
Organism: Homo sapiens
Interactions: 90
UniProt ID: P48436

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818793

EP300
Histone acetyltransferase p300

4

20

Small-scale

0.676

High

818834

FBXW7
F-box/WD repeat-containing protein 7

3

18

Small-scale

0.664

High

818782

SOX9
Transcription factor SOX-9

1

19

Small-scale

0.647

High

818817

PB1
Protein polybromo-1

1

20

High-throughput

0.618

High

818837

CIC
Protein capicua homolog

1

19

High-throughput

0.618

High

818802

RUNX2
Runt-related transcription factor 2

2

8

Small-scale

0.602

High

818783

GSK3B
Glycogen synthase kinase-3 beta

2

11

Small-scale

0.595

High

818787

UBC9
SUMO-conjugating enzyme UBC9

2

10

Small-scale

0.595

High

818843

ZRAN1
Ubiquitin thioesterase ZRANB1

2

15

Small-scale

0.584

High

818796

STF1
Steroidogenic factor 1

1

20

Small-scale

0.573

High

818833

MED12
Mediator of RNA polymerase II transcription subunit 12

1

20

Small-scale

0.573

High

443150

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.561

High

818805

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.561

High

818831

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

14

Small-scale

0.561

High

265123

MAF
Transcription factor Maf

1

0

Small-scale

0.549

High

818786

RCAN1
Calcipressin-1

1

1

High-throughput

0.541

High

568584

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

6

Small-scale

0.527

High

818795

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

818806

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

17

Small-scale

0.512

High

727488

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.501

High

818789

ELF3
ETS-related transcription factor Elf-3

1

20

Small-scale

0.501

High

818823

CR3L4
Cyclic AMP-responsive element-binding protein 3-like protein 4

1

11

Small-scale

0.501

High

818846

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.494

High

131701

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

135093

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

146178

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

152611

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164200

ZN609
Zinc finger protein 609

1

20

High-throughput

0.479

High

183081

KDM6A
Lysine-specific demethylase 6A

1

14

High-throughput

0.479

High

244095

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

312036

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

17

Small-scale

0.479

High

641336

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

764606

CUX1
Homeobox protein cut-like 1

1

20

High-throughput

0.479

High

818784

SMCA2
Probable global transcription activator SNF2L2

1

20

High-throughput

0.479

High

818785

SMCA4
Transcription activator BRG1

1

20

High-throughput

0.479

High

818788

H31
Histone H3.1

1

20

High-throughput

0.479

High

818790

SMAD3
Mothers against decapentaplegic homolog 3

1

17

Small-scale

0.479

High

818791

H33
Histone H3.3

1

20

High-throughput

0.479

High

818792

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

818794

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

5

High-throughput

0.479

High

818797

CUL1
Cullin-1

1

15

Small-scale

0.479

High

818798

CUL2
Cullin-2

1

15

Small-scale

0.479

High

818799

CUL3
Cullin-3

1

15

Small-scale

0.479

High

818800

CUL4A
Cullin-4A

1

15

Small-scale

0.479

High

818801

CUL4B
Cullin-4B

1

15

Small-scale

0.479

High

818803

KEAP1
Kelch-like ECH-associated protein 1

1

6

Small-scale

0.479

High

818804

NCOA6
Nuclear receptor coactivator 6

1

20

High-throughput

0.479

High

818807

SMAD2
Mothers against decapentaplegic homolog 2

1

17

Small-scale

0.479

High

818808

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

818810

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

818811

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

20

High-throughput

0.479

High

818813

UBN2
Ubinuclein-2

1

20

High-throughput

0.479

High

818814

PAXI1
PAX-interacting protein 1

1

20

High-throughput

0.479

High

818815

SCX
Basic helix-loop-helix transcription factor scleraxis

1

13

Small-scale

0.479

High

818816

MAVS
Mitochondrial antiviral-signaling protein

1

19

Small-scale

0.479

High

818818

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

818819

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

818820

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

818821

KDM2B
Lysine-specific demethylase 2B

1

6

High-throughput

0.479

High

818822

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.479

High

818824

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

818825

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

11

High-throughput

0.479

High

818826

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

818827

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

818828

CBP
CREB-binding protein

1

20

High-throughput

0.479

High

818829

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

High-throughput

0.479

High

818830

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

20

High-throughput

0.479

High

818832

CUL5
Cullin-5

1

15

Small-scale

0.479

High

818835

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

16

High-throughput

0.479

High

818836

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

818838

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

818839

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

818841

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

High-throughput

0.479

High

818845

TRPS1
Zinc finger transcription factor Trps1

1

20

High-throughput

0.479

High

818847

PRR12
Proline-rich protein 12

1

20

High-throughput

0.479

High

818848

UBP18
Ubl carboxyl-terminal hydrolase 18

1

16

Small-scale

0.479

High

818849

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.479

High

818850

FBW1A
F-box/WD repeat-containing protein 1A

1

20

Small-scale

0.479

High

818851

ZN281
Zinc finger protein 281

1

16

High-throughput

0.479

High

818852

FBX7
F-box only protein 7

1

2

Small-scale

0.479

High

818853

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.479

High

818854

NCOA3
Nuclear receptor coactivator 3

1

20

High-throughput

0.479

High

147059

NEMP1
Nuclear envelope integral membrane protein 1

1

1

High-throughput

0.437

High

483385

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

9

High-throughput

0.437

High

818812

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

818840

KLHL1
Kelch-like protein 1

1

6

Small-scale

0.437

High

818842

KLH13
Kelch-like protein 13

1

7

Small-scale

0.437

High

818844

KLHL3
Kelch-like protein 3

1

6

Small-scale

0.437

High

818809

WLS
Protein wntless homolog

2

0

Small-scale

0.304

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024