HitPredict

Interactor 1: LEUC (P07264)
3-isopropylmalate dehydratase (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)
Gene: LEU1

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 16429126
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 779 Sc			1 613
+	Sc
		425099 LEUC_YEAST (1-779): 0: 978: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		584168 ACON_YEAST (8-723): 0: 704: 22.78		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510208 ACON_YEAST (8-723): 0: 704: 22.78		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		762737 ACON2_YEAST (8-726): 0: 691: 22.01		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511362 ACON2_YEAST (8-726): 0: 691: 22.01		SSB1_YEAST (1-613): 0: 1118: 99.35
+	At
		612314 ACO2M_ARATH (10-712): 0: 748: 19.42		HS701_ARATH (1-612): 0: 890: 57.96
+	Hs
		503427 ACOHC_HUMAN (10-709): 0: 728: 19.74		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		768890 LYS4_YEAST (9-671): 3.42e-156: 472: 23.28		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		511948 LYS4_YEAST (9-671): 3.42e-156: 472: 23.28		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		504641 ACON_HUMAN (8-727): 0: 685: 22.27		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		449901 ACON_YEAST (8-723): 0: 704: 22.78		HSP73_YEAST (9-611): 0: 677: 60.66