HitPredict

Interactor 1: PROF (P07274)
Profilin
Gene: PFY1

Interactor 2: BNR1 (P40450)
BNI1-related protein 1
Gene: BNR1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.647

Property	Details
Experiments	11489916, 10688190, 9184220
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1903475 - mitotic actomyosin contractile ring assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Sc			1 1375
+	Sp
		764559 PROF_SCHPO (1-126): 3.51e-49: 154: 52.76		CDC12_SCHPO (92-1375): 0: 594: 21.01
+	Hs
		314830 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		FMNL1_HUMAN (353-1365): 8.69e-151: 487: 15.48
+	Hs
		314847 PROF2_HUMAN (3-126): 4.02e-34: 117: 23.74		FMNL1_HUMAN (353-1365): 8.69e-151: 487: 15.48
+	Hs
		430307 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		FMNL2_HUMAN (353-1366): 1.64e-142: 465: 15.92
+	Hs
		237549 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		DIAP1_HUMAN (345-1372): 3.6e-140: 463: 17.71
+	Hs
		237564 PROF2_HUMAN (3-126): 4.02e-34: 117: 23.74		DIAP1_HUMAN (345-1372): 3.6e-140: 463: 17.71
+	Dm
		639194 PROF_DROME (1-126): 4.63e-50: 157: 39.37		Q8IRY0_DROME (478-1355): 1.32e-124: 417: 16.00
+	Dd
		640684 PROF2_DICDI (1-123): 1.18e-41: 135: 39.02		FORH_DICDI (331-1332): 1.01e-122: 411: 13.35
+	Hs
		430352 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		DIAP3_HUMAN (856-1372): 1.62e-104: 362: 18.37
+	Dm
		639180 PROF_DROME (1-126): 4.63e-50: 157: 39.37		DIA_DROME (827-1327): 6.55e-94: 330: 17.45
+	Hs
		243087 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		DIAP2_HUMAN (823-1352): 1.31e-99: 346: 18.89
+	Hs
		430404 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		FHOD1_HUMAN (523-1374): 9.13e-99: 345: 11.79
+	At
		221287 PRF3_ARATH (1-125): 7.62e-54: 168: 29.77		FH4_ARATH (859-1288): 2.77e-83: 292: 16.11
+	Dm
		639185 PROF_DROME (1-126): 4.63e-50: 157: 39.37		CAPU_DROME (591-1309): 1.97e-84: 301: 15.29
+	Hs
		430356 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		FMN2_HUMAN (825-1287): 1.2e-91: 329: 18.69
+	At
		221286 PRF2_ARATH (1-125): 1.06e-50: 158: 30.53		FH4_ARATH (859-1288): 2.77e-83: 292: 16.11
+	Hs
		430197 PROF1_HUMAN (3-126): 1.91e-38: 128: 25.18		INF2_HUMAN (841-1364): 4.91e-83: 300: 17.54
+	Hs
		714970 PROF2_HUMAN (3-126): 4.02e-34: 117: 23.74		INF2_HUMAN (841-1364): 4.91e-83: 300: 17.54
+	Sc
		425515 PROF_YEAST (1-126): 9.67e-51: 158: 100.00		BNI1_YEAST (187-727): 1.72e-62: 237: 14.58
+	Ce
		109520 PROF1_CAEEL (1-126): 1.09e-37: 125: 26.52		H2KYI3_CAEEL (852-1315): 1.49e-47: 188: 15.75