HitPredict

Interactor 1: ANXA2 (P07355)
Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)
Gene: ANXA2

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21280222
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 317
+	Hs
		451777 ANXA4_HUMAN (25-339): 5.88e-173: 484: 49.52		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		533963 ANXA8_HUMAN (26-338): 1.48e-162: 458: 46.33		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		444862 ANXA5_HUMAN (24-339): 5.27e-160: 451: 46.20		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		376190 ANXA1_HUMAN (1-338): 4.33e-159: 450: 50.72		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		427645 ANXA2_HUMAN (1-339): 3.16e-174: 488: 100.00		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		281983 ANXA9_HUMAN (2-339): 3.33e-80: 249: 40.71		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		589163 ANXA7_HUMAN (191-338): 7.11e-30: 120: 28.19		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00