Interactor 1: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Interactor 2: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 36964131
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Calpain_III~EF-hand_8, Calpain_III~Peptidase_C2, EF-hand_8~EF-hand_8, Peptidase_C2~Peptidase_C2
Common GO terms GO:0001533 - cornified envelope
GO:0004198 - calcium-dependent cysteine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
and 18 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 714
Hs

1 714
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Last updated: 15 Jul 2024