HitPredict

Interactor 1: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Interactor 2: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 714 Hs			1 739
+	Hs
		595836 CAN3_HUMAN (10-714): 0: 853: 46.18		TITIN_HUMAN (602-739): 2.77e-09: 63.1: 17.24
+	Hs
		581469 SORCN_HUMAN (540-712): 5.06e-63: 210: 31.21		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00
+	Hs
		385838 CPNS1_HUMAN (510-714): 2.62e-56: 194: 43.60		VCAM1_HUMAN (1-739): 2.2e-152: 462: 100.00