HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	16027165, 20856200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0015630 - microtubule cytoskeleton GO:0032991 - protein-containing complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 480
+	Hs
		681781 TBB4B_HUMAN (1-427): 0: 707: 98.36		AKT1_HUMAN (1-480): 0: 586: 100.00
+	Dm
		1213355 Q8MST5_DROME (1-443): 0: 695: 86.91		AKT1_DROME (3-474): 0: 523: 60.37
+	Dm
		445198 TBB3_DROME (1-442): 0: 694: 89.29		AKT1_DROME (3-474): 0: 523: 60.37
+	Hs
		428148 TBB5_HUMAN (1-429): 0: 709: 100.00		KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77
+	Hs
		933762 TBB4B_HUMAN (1-427): 0: 707: 98.36		KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77
+	Hs
		1037424 TBB3_HUMAN (1-444): 0: 712: 92.57		KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25
+	Hs
		428478 TBB5_HUMAN (1-429): 0: 709: 100.00		KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25
+	Hs
		969091 TBB8_HUMAN (1-427): 0: 702: 89.70		KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77
+	Hs
		934009 TBB4B_HUMAN (1-427): 0: 707: 98.36		KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25
+	Hs
		381125 TBB4A_HUMAN (1-427): 0: 702: 97.42		KS6B1_HUMAN (132-479): 4.01e-147: 432: 43.75
+	Hs
		1312829 TBB6_HUMAN (1-432): 0: 703: 92.13		KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25
+	Hs
		568654 TBB3_HUMAN (1-444): 0: 712: 92.57		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		568659 TBB2A_HUMAN (1-430): 0: 704: 96.98		KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53
+	Hs
		784079 TBB2B_HUMAN (1-430): 0: 707: 97.44		KPCI_HUMAN (139-474): 7.46e-101: 316: 45.53
+	Hs
		784006 TBB2A_HUMAN (1-430): 0: 704: 96.98		KPCI_HUMAN (139-474): 7.46e-101: 316: 45.53
+	Hs
		1037238 TBB3_HUMAN (1-444): 0: 712: 92.57		KS6A2_HUMAN (85-452): 6.82e-94: 301: 25.39
+	Hs
		1037241 TBB3_HUMAN (1-444): 0: 712: 92.57		KS6A1_HUMAN (85-407): 6.15e-92: 296: 26.39