Protein: IFIT1
Antiviral innate immune response effector IFIT1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56) (Interferon-induced protein with tetratricopeptide repeats 1)

Gene: IFIT1
Organism: Homo sapiens
Interactions: 72
UniProt ID: P09914

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004857 - enzyme inhibitor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

166749

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

7

14

High-throughput

0.977

High

488092

IFIT2
Interferon-induced protein with tetratricopeptide repeats 2

4

15

High-throughput

0.916

High

488176

IFIT5
Interferon-induced protein with tetratricopeptide repeats 5

2

17

High-throughput

0.806

High

461058

HS90A
Heat shock protein HSP 90-alpha

1

9

High-throughput

0.691

High

467990

HS90B
Heat shock protein HSP 90-beta

1

9

High-throughput

0.691

High

488179

IFT1B
Protein IFIT1 homolog B

1

17

High-throughput

0.691

High

378313

IFNA5
Interferon alpha-5

3

11

High-throughput

0.667

High

378325

IFN14
Interferon alpha-14

3

11

High-throughput

0.667

High

488154

IFNA8
Interferon alpha-8

3

11

High-throughput

0.667

High

488177

IRF3
Interferon regulatory factor 3

3

8

Small-scale

0.640

High

378261

IFN10
Interferon alpha-10

2

11

High-throughput

0.628

High

378281

IFN21
Interferon alpha-21

2

11

High-throughput

0.628

High

488184

PHAR4
Phosphatase and actin regulator 4

2

7

High-throughput

0.628

High

488146

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.618

High

425273

ISG15
Ubiquitin-like protein ISG15

2

9

Small-scale

0.601

High

488160

EIF3E
Eukaryotic translation initiation factor 3 subunit E

2

1

Small-scale

0.584

High

378269

IFNA7
Interferon alpha-7

1

11

High-throughput

0.536

High

425761

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

4

High-throughput

0.536

High

425871

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

4

High-throughput

0.536

High

428042

RLA1
Large ribosomal subunit protein P1

1

1

High-throughput

0.536

High

462209

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

6

High-throughput

0.536

High

472416

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

High-throughput

0.536

High

477899

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.536

High

480018

RU1C
U1 small nuclear ribonucleoprotein C

1

3

High-throughput

0.536

High

485552

RU2A
U2 small nuclear ribonucleoprotein A'

1

7

High-throughput

0.536

High

488147

PYC
Pyruvate carboxylase, mitochondrial

1

4

High-throughput

0.536

High

488148

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.536

High

488149

PABP1
Polyadenylate-binding protein 1

1

14

High-throughput

0.536

High

488150

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

488151

NUCL
Nucleolin

1

14

High-throughput

0.536

High

488152

TFEB
Transcription factor EB

1

3

High-throughput

0.536

High

488153

S10A7
Protein S100-A7

1

3

High-throughput

0.536

High

488163

RUXE
Small nuclear ribonucleoprotein E

1

2

High-throughput

0.536

High

488164

RUXF
Small nuclear ribonucleoprotein F

1

6

High-throughput

0.536

High

488165

SMD1
Small nuclear ribonucleoprotein Sm D1

1

9

High-throughput

0.536

High

488166

SMD2
Small nuclear ribonucleoprotein Sm D2

1

3

High-throughput

0.536

High

488167

SMD3
Small nuclear ribonucleoprotein Sm D3

1

9

High-throughput

0.536

High

488168

YBOX1
Y-box-binding protein 1

1

8

High-throughput

0.536

High

488169

DCD
Dermcidin

1

1

High-throughput

0.536

High

488173

ILF2
Interleukin enhancer-binding factor 2

1

5

High-throughput

0.536

High

488174

ACACA
Acetyl-CoA carboxylase 1

1

4

High-throughput

0.536

High

488175

PABP4
Polyadenylate-binding protein 4

1

14

High-throughput

0.536

High

488183

STING
Stimulator of interferon genes protein

1

1

Small-scale

0.536

High

488188

TOE1
Target of EGR1 protein 1

1

2

High-throughput

0.536

High

488189

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

4

High-throughput

0.536

High

488192

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

4

High-throughput

0.536

High

488193

MOV10
Helicase MOV-10

1

1

High-throughput

0.536

High

471765

RU2B
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.489

High

403762

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

488155

CTNB1
Catenin beta-1

1

6

Small-scale

0.479

High

488156

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

4

Small-scale

0.479

High

488158

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

7

Small-scale

0.479

High

488159

STAT2
Signal transducer and activator of transcription 2

1

4

Small-scale

0.479

High

488162

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

4

High-throughput

0.479

High

488170

IRF9
Interferon regulatory factor 9

1

8

Small-scale

0.479

High

488172

EP300
Histone acetyltransferase p300

1

14

High-throughput

0.479

High

488178

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.479

High

488180

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.479

High

488181

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

488182

MAVS
Mitochondrial antiviral-signaling protein

1

8

High-throughput

0.479

High

488185

CGAS
Cyclic GMP-AMP synthase

1

4

High-throughput

0.479

High

488186

SAP25
Histone deacetylase complex subunit SAP25

1

2

Small-scale

0.479

High

488187

FUBP2
Far upstream element-binding protein 2

1

8

Small-scale

0.479

High

488190

RIOK1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

488194

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

8

High-throughput

0.479

High

488195

TES
Testin

1

3

High-throughput

0.479

High

488161

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

4

High-throughput

0.445

High

488171

TAGL
Transgelin

1

1

High-throughput

0.445

High

488157

CDK9
Cyclin-dependent kinase 9

1

6

Small-scale

0.437

High

488196

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

402825

ANXA1
Annexin A1

1

5

Small-scale

0.408

High

488191

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025