HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: ARL2 (P36404)
ADP-ribosylation factor-like protein 2
Gene: ARL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0015630 - microtubule cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 184
+	Dm
		989450 TBB1_DROME (1-429): 0: 705: 96.50		ARL2_DROME (1-184): 2.09e-85: 250: 75.54
+	Dm
		989452 Q8MST5_DROME (1-443): 0: 695: 86.91		ARL2_DROME (1-184): 2.09e-85: 250: 75.54
+	Hs
		734457 TBB4B_HUMAN (1-427): 0: 707: 98.36		ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00
+	Hs
		734485 TBB2B_HUMAN (1-430): 0: 707: 97.44		ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00
+	Hs
		734463 TBB2A_HUMAN (1-430): 0: 704: 96.98		ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00
+	Hs
		381137 TBB4A_HUMAN (1-427): 0: 702: 97.42		ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00
+	Hs
		734468 TBB8_HUMAN (1-427): 0: 702: 89.70		ARL2_HUMAN (1-184): 2.36e-74: 222: 100.00
+	Dm
		897432 TBB2_DROME (1-430): 0: 697: 95.58		ARF1_DROME (1-178): 1.6e-73: 220: 46.37
+	Hs
		895072 TBB2A_HUMAN (1-430): 0: 704: 96.98		RAB2A_HUMAN (11-183): 9.46e-65: 199: 21.35