Protein: RLA1
Large ribosomal subunit protein P1A (P1A) (60S acidic ribosomal protein P1-alpha) (A1) (L12eIIA) (YP1alpha)

Gene: RLA1, RPP1A
Organism: Saccharomyces cerevisiae S288C
Interactions: 132
UniProt ID: P05318

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0006414 - translational elongation
GO:0022625 - cytosolic large ribosomal subunit
GO:0030295 - protein kinase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

383036

RLA4
Large ribosomal subunit protein P2B

8

8

Small-scale

0.961

High

427048

RLA0
Large ribosomal subunit protein uL10

6

7

Small-scale

0.949

High

427531

RLA3
Large ribosomal subunit protein P1B

3

4

Small-scale

0.829

High

427504

RLA1
Large ribosomal subunit protein P1A

1

4

Small-scale

0.618

High

427505

RLA2
Large ribosomal subunit protein P2A

1

8

Small-scale

0.618

High

427548

TF2B
Transcription initiation factor IIB

2

3

High-throughput

0.561

High

427572

IF2P
Eukaryotic translation initiation factor 5B

2

1

Small-scale

0.558

High

427612

RQC1
Ribosome quality control complex subunit 1

2

1

Small-scale

0.521

High

427556

SPT7
SAGA complex subunit SPT7

1

4

High-throughput

0.489

High

427562

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

3

High-throughput

0.489

High

427567

RT107
Regulator of Ty1 transposition protein 107

1

2

Small-scale

0.489

High

427589

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

1

High-throughput

0.489

High

427606

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.489

High

427607

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

1

High-throughput

0.489

High

427626

SUS1
SAGA complex subunit SUS1

1

2

High-throughput

0.489

High

154097

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.479

High

394086

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.479

High

409814

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

427506

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

427507

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.479

High

427508

RL6B
Large ribosomal subunit protein eL6B

1

3

High-throughput

0.479

High

427509

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.479

High

427510

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

427511

RL36A
Large ribosomal subunit protein eL36A

1

3

High-throughput

0.479

High

427512

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.479

High

427513

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

427514

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

427520

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.479

High

427521

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

427522

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

427523

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

427525

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.479

High

427526

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.479

High

427527

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

427528

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

427529

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

427530

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.479

High

427532

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.479

High

427535

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.479

High

427536

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

427537

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.479

High

427546

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

427547

RL16A
Large ribosomal subunit protein uL13A

1

3

High-throughput

0.479

High

427550

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.479

High

427558

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

427561

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

427566

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

427569

STM1
Suppressor protein STM1

1

1

High-throughput

0.479

High

427571

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

427574

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.479

High

427575

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

427577

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

427578

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

427582

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

427585

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

427586

RL4B
Large ribosomal subunit protein uL4B

1

3

High-throughput

0.479

High

427591

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

427599

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

427601

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.479

High

427603

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

427617

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

427621

RL7B
Large ribosomal subunit protein uL30B

1

4

High-throughput

0.479

High

427624

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

427625

RL13A
Large ribosomal subunit protein eL13A

1

3

High-throughput

0.479

High

414959

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

427524

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.458

High

427590

LSG1
Large subunit GTPase 1

1

0

High-throughput

0.458

High

427515

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.457

High

427538

CSK22
Casein kinase II subunit alpha'

1

3

Small-scale

0.457

High

427551

EF2
Elongation factor 2

1

2

Small-scale

0.457

High

391964

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.437

High

427516

SC160
Protein SCP160

1

2

High-throughput

0.437

High

427519

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.437

High

427534

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

427541

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.437

High

427542

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

427545

SPB4
ATP-dependent rRNA helicase SPB4

1

4

High-throughput

0.437

High

427549

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.437

High

427552

ZUO1
Zuotin

1

3

High-throughput

0.437

High

427554

IXR1
Intrastrand cross-link recognition protein

1

1

Small-scale

0.437

High

427560

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

427564

ATG8
Autophagy-related protein 8

1

5

High-throughput

0.437

High

427570

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

427573

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.437

High

427576

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

427579

ELP2
Elongator complex protein 2

1

1

High-throughput

0.437

High

427580

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

427583

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

427593

H1
Histone H1

1

1

High-throughput

0.437

High

427594

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

427595

JJJ1
J protein JJJ1

1

2

High-throughput

0.437

High

427596

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.437

High

427605

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

427608

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

427609

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.437

High

427610

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.437

High

427614

ELP1
Elongator complex protein 1

1

1

High-throughput

0.437

High

427620

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

427622

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

427623

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

427600

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

427568

SPT8
SAGA complex subunit SPT8

1

1

High-throughput

0.407

High

427587

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

2

High-throughput

0.407

High

427588

SPT20
SAGA complex subunit SPT20

1

1

High-throughput

0.407

High

427611

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.407

High

427540

TRX2
Thioredoxin-2

1

0

High-throughput

0.282

High

427581

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.269

Low

401800

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

427517

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.249

Low

427518

TFS2
Transcription elongation factor S-II

1

0

High-throughput

0.249

Low

427533

TIR1
Cold shock-induced protein TIR1

1

0

High-throughput

0.249

Low

427539

KCC2
Calcium/calmodulin-dependent protein kinase II

1

0

High-throughput

0.249

Low

427543

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.249

Low

427544

SYP1
Suppressor of yeast profilin deletion

1

0

High-throughput

0.249

Low

427553

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.249

Low

427555

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.249

Low

427557

YKH1
Uncharacterized oxidoreductase YKL071W

1

0

High-throughput

0.249

Low

427559

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

427563

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.249

Low

427565

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

427584

PUS4
tRNA pseudouridine synthase 4

1

0

High-throughput

0.249

Low

427592

SOL4
6-phosphogluconolactonase 4

1

0

High-throughput

0.249

Low

427597

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

427598

FAP1
FKBP12-associated protein 1

1

0

High-throughput

0.249

Low

427604

ELP3
Elongator complex protein 3

1

0

High-throughput

0.249

Low

427613

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.249

Low

427615

ETT1
Enhancer of translation termination 1

1

0

High-throughput

0.249

Low

427616

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

427619

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

427602

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.232

Low

427618

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025