HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19380743, 12577067
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 217
+	Hs
		924548 TBB3_HUMAN (1-444): 0: 712: 92.57		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924460 TBB4B_HUMAN (1-427): 0: 707: 98.36		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924836 TBB6_HUMAN (1-432): 0: 703: 92.13		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		411549 TBB5_HUMAN (1-429): 0: 709: 100.00		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411668 TBB4B_HUMAN (1-427): 0: 707: 98.36		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		428198 TBB5_HUMAN (1-429): 0: 709: 100.00		PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93
+	Hs
		933801 TBB4B_HUMAN (1-427): 0: 707: 98.36		PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93
+	Hs
		548704 TBB3_HUMAN (1-444): 0: 712: 92.57		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		428001 TBB5_HUMAN (1-429): 0: 709: 100.00		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		548681 TBB4B_HUMAN (1-427): 0: 707: 98.36		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		381112 TBB4A_HUMAN (1-427): 0: 702: 97.42		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		427991 TBB5_HUMAN (1-429): 0: 709: 100.00		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		381102 TBB4A_HUMAN (1-427): 0: 702: 97.42		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47